TABLE 2.

Toxicity of Cyt1A toward C. quinquefasciatus selected or nonselected with Cyt1A from B. thuringiensis subsp. israelensis for 20 generations

Mosquito straina	Toxin tested	Generation	LC50 (μg/ml), FLb	LC95 FL (μg/ml), FL	Resistance ratio at:
					LC50	LC95
SynParent	Cyt1A	4	14.1, 10.5-18.2	504, 336-854	1.0	1.0
Cyt1A	Cyt1A	4	31.0, 15.0-64.0	289, 70.5-1,206	2.2	0.6
SynParent	Cyt1A	7	15.9, 5.96-42.4	123, 20.7-742	1.0	1.0
Cyt1A	Cyt1A	7	15.1, 12.4-17.9	162, 121-234	0.95	1.3
SynParent	Cyt1A	9	37.5, 15.8-88.9	1,412, 206-9,857	1.0	1.0
Cyt1A	Cyt1A	9	28.2, 11.0-72.1	668, 100-4,467	0.8	0.5
SynParent	Cyt1A	13	16.2, 13.8-18.9	152, 116-213	1.0	1.0
Cyt1A	Cyt1A	13	15.0, 6.75-33.3	181, 40.4-821	0.9	1.2
SynParent	Cyt1A	17	7.90, 6.52-9.49	145, 104-221	1.0	1.0
Cyt1A	Cyt1A	17	38.8, 22.9-65.7	883, 328-2,453	4.9	6.1
SynParent	Cyt1A	20	6.25, 2.96-13.1	50.4, 13.9-184	1.0	1.0
Cyt1A	Cyt1A	20	32.7, 8.47-125	12,243, 189-818,272	5.2	242

^aSynParent, unselected; Cyt1A, Cyt1A selected.

^bFL, fiducial limits.