Table 1.
Strains | 2-AA IC50 [μM] | Maximal DHQ production [%] | HQNO IC50 [μM] | Signal moleculesa IC50 [μM] | Overall IC50 [μM] |
---|---|---|---|---|---|
PA14 wt | 1.3 (1.1-1.2)b | 330 ± 12c @ 1 μM | 1.2 (1.1-1.3)b | 1.1 (1.0-1.2)b | 1.2 (1.1-1.3)b |
PA14 pqsH mutant | 0.19 (0.16-0.22)b | 304 ± 2c @ 0.2 μM | 0.27 (0.25-0.30)b | 0.27 (0.25-0.30)b | 0.32 (0.30-0.34)b |
aIn PA14 wt referred to sum of HHQ and PQS concentrations; in PA14 pqsH mutant referred to HHQ concentration. b95% Confidence Intervals. cStandard Error of the Mean intervals.