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. 2017 May 17;8:15160. doi: 10.1038/ncomms15160

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Copyright © 2017, The Author(s)

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Stage V gametocyte cultures were exposed to 2 μM of TCMDC-141070 and 1 μM of the five remaining compounds for 48 h. The percentage inhibition was determined compared to DMSO-treated controls. Compounds were then progressed into SMFA to further determine the transmission blocking in mosquitoes. Each bar represents mean value of two (TCMDC-125345, TCMDC-141698, TCMDC-123767, TCMDC-141154) or three (TCMDC-141070, TCMDC-124559) independent replicates with s.d.