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. 2017 May 5;37(6):3167–3174. doi: 10.3892/or.2017.5630

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Copyright: © Ye et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — PCDH10 inhibits the PI3K/Akt signaling pathway. (A) The expression level of proteins in the Akt signaling pathway examined with western blot analysis. (B) The quantitative analysis of the expression level. (C) Co-IP assay indicates the interaction between PCDH10 and PI3K. (D) The network displaying the inhibition of the PI3K/Akt signaling pathway by PCDH10. PCDH10: cells transfected with plasmid PCDH10; vector: cells transfected with the plasmid vector, *P<0.05 compared to the vector. PCDH10, protocadherin10; PI3K, phosphoinositide 3-kinase; Co-IP, co-immunoprecipitation.