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. 2017 May 4;37(6):3181–3188. doi: 10.3892/or.2017.5628

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Copyright: © Panagopoulos et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Interphase FISH for the detection of a SETD2-NF1 fusion gene. (A) The positions of the clones RP11-565B06 (chr3:46962826-47104129) and RP11-380M12 (chr3:47033474-47226748) are indicated in chromosome band 3p21.31. The clones contained the SETD2 gene and were labeled with red. (B) The positions of the clones RP11-518B17 (chr17:26576215-26749754) and RP11-592F3 (chr17:26705272-26874157) are indicated in chromosome band 17q11.2. The clones contained part of the NF1 gene and were labeled with green. (C) Interphase FISH showing nucleus with a green signal, a red signal, and a yellow signal. The yellow signal corresponds to the SETD2-NF1 fusion gene. The fact that there is only one yellow signal indicates that there is no reciprocal fusion.