TABLE 3.
Antifungal agent | Test method | No. of isolates with MIC/MEC (mg/liter) of: |
GM MICa | MIC50/MEC50a | MIC90/MEC90a | MIC rangea | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
≤0.008 | 0.015 | 0.03 | 0.06 | 0.12 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | 32 | ≥64 | ||||||
Itraconazole | BMD | 35 | 4 | 5 | 2 | 1 | 1 | 2 | 0.01 | 0.008 | 0.06 | 0.008–0.5 | |||||||
Voriconazole | BMD | 37 | 5 | 5 | 3 | 0.01 | 0.008 | 0.03 | 0.008–0.06 | ||||||||||
Posaconazole | BMD | 32 | 8 | 4 | 4 | 2 | 0.01 | 0.008 | 0.06 | 0.008–1 | |||||||||
Fluconazole | BMD | 34 | 8 | 5 | 1 | 1 | 1 | 0.18 | 0.12 | 0.5 | 0.12–8 | ||||||||
Caspofungin | BMD | 3 | 20 | 23 | 3 | 1 | 1.67 | 2 | 2 | 0.25–8 | |||||||||
Micafungin | BMD | 1 | 1 | 20 | 11 | 13 | 4 | 1.72 | 2 | 4 | 0.03–8 | ||||||||
Anidulafungin | BMD | 13 | 32 | 5 | 1.72 | 2 | 2 | 1–4 | |||||||||||
Flucytosine | BMD | 50 | 208.42 | 256 | 256 | 64–256 | |||||||||||||
Amphotericin B | Etest | 24 | 7 | 3 | 6 | 7 | 2 | 1 | 0.01 | 0.03 | 0.25 | 0.002–1 | |||||||
Itraconazole | Etest | 36 | 1 | 10 | 1 | 1 | 1 | 0.01 | 0.006 | 0.03 | 0.002–0.5 | ||||||||
Voriconazole | Etest | 50 | 0.001 | 0.002 | 0.002 | 0.002–0.008 | |||||||||||||
Posaconazole | Etest | 48 | 1 | 1 | 0.002 | 0.002 | 0.004 | 0.002–0.03 |
All MICs are in milligrams per milliliter.