TABLE 4.
Fe-S biosynthesis systems in select bacterial strains
| Bacterial species | Fe-S assembly machinery | Fe-S biogenesis system predicted to be essential | Reference |
|---|---|---|---|
| Acinetobacter baumanniia | Isc | Yes | 83 |
| Bacillus subtilis | Suf | Yes | 84 |
| Bacteroides fragilis | Suf | Yes | 85 |
| Burkholderia pseudomallei | Suf and Isc | Yesc | 86 |
| Campylobacter jejuni | Nif | Yes | 87 |
| Clostridium difficile | Suf | Yes | 88 |
| Enterococcus faecalisa | Suf | Yesb | 89 |
| Escherichia coli | Suf and Isc | No | 61 |
| Francisella novicida | Suf | Yes | 90 |
| Haemophilus influenzae | Isc | Yes | 91 |
| Helicobacter pylori | Nif | Yes | 92 |
| Klebsiella pneumoniaea | Suf, Nif and Isc | No | 60 |
| Mycobacterium tuberculosis | Suf | Yes | 93 |
| Porphyromonas gingivalis | Suf | Yes | 94 |
| Pseudomonas aeruginosaa | Isc | Yes | 95 |
| Salmonella enterica | Suf and Isc | No | 96 |
| Staphylococcus aureusa | Suf | Yes | 22 |
| Streptococcus pneumoniae | Suf | Yes | 97 |
| Streptococcus pyogenes | Suf | Yes | 98 |
| Vibrio cholerae | Isc | Yes | 99 |
a
ESKAPE pathogen, capable of escaping the biocidal effects of antibiotics.
b
Limited data set.
c
The IscS cysteine desulfurase is predicted to be essential.