Table 1.

Strategies to improve engraftment and immune recovery

Agent	Mechanism	Author	n	Days to ANC > 500	Current trial
Nicotinamide	Inhibit enzymes that require NAD+	Horwitz et al. [17]	11	13	NCT02730299
Notch	Inhibit differentiation	Delaney et al. [16]	10	16	NCT01690520
Mesenchymal stem cells	Improve stroma	De Lima et al. [15]	31	15	NCT01854567
Prostaglandin E2	Homing	Cutler et al. [11]	12	17
FT‐VI	Fucosylation	Popat et al. [18]	7	14	NCT01471067
Sitagliptin	DPP‐IV inhibition	Farag et al. 45	24	21	NCT01720264
Intrabone marrow	Homing	Kurita et al. [21]	15	17

Abbreviations: ANC, absolute neutrophil count; FT, fucosyltransferase; DPP, dipeptidyl peptidase; NAD+, nicotinamide adenine dinucleotide.