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. 2016 Aug 8;6(1):316–329. doi: 10.5966/sctm.2016-0087

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© 2016 The Authors Stem Cells Translational Medicine published by Wiley Periodicals, Inc. on behalf of AlphaMed Press

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Stem cells homing to the lesion site in a brain injury model. (A): Systematic presentation of TBI induction, MSC administration, and sacrifice of animals for IHC. The black rectangle in MRI represents the injury site where IHC was carried out. Fluorescent figure represents stem cells homing to the site of injury on D3 (B) and D7 (C). Red fluorescence indicates PKH26 membrane dye of administered MSCs, and blue fluorescence indicates nuclear staining dye Hoechst 33342. Scale bar = 100 µm. Abbreviations: D, day; IHC, immunohistochemistry; MRI, magnetic resonance imagining; MSC, mesenchymal stem cell; TBI, traumatic brain injury.