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. 2016 Oct 7;6(3):830–839. doi: 10.5966/sctm.2016-0009

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© 2016 The Authors Stem Cells Translational Medicine published by Wiley Periodicals, Inc. on behalf of AlphaMed Press

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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bELE effectively inhibited tumorigenesis of mouse model. (A, B): Growth curves of tumors formed by U87 and U87/GSLCs. The five groups were as follows: the control group, the solvent‐only injected group, and three other groups treated with TMZ, bELE, and TMZ/bELE. (C): The mice were sacrificed when the tumor burden jeopardized their survival, and the tumor masses were dissected. (D): Statistical analysis of tumor weight. ∗, p < .05; ∗∗, p < .01; n = 5. Abbreviations: bELE, β‐elemene; CTR, control; GSLCs, glioma stem‐like cells; TMZ, temozolomide.