Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Feb 3;6(3):819–829. doi: 10.1002/sctm.16-0335

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 The Authors Stem Cells Translational Medicine published by Wiley Periodicals, Inc. on behalf of AlphaMed Press

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

PMC Copyright notice

Gamma‐secretase inhibitor IX (GSI) inhibits CD44⁺ cancer stem cells xenograft tumor growth. (A): Pictures of mice taken after 4 weeks of treatment with indicated therapies. The arrows showing the xenograft tumors (n = 5/group). (B): H&E stainings of corresponding tumors (10× & 20× magnification), showing necrosis under GSI therapy. (C): Tumor growth curves of all right and left flanks tumors under indicated treatments. (D): Mouse weight curves for indicated therapies. Quantification of (E): tumor weight (F): Ki67 staining of the xenograft tumors according to different therapy groups. *p < .05, **p < .005. Abbreviation: GSI, gamma‐secretase inhibitor IX.