Table 6.
Quality‐of‐life indicators
| Groups | ||||||
|---|---|---|---|---|---|---|
| EBV (n = 5) | EBV + MSC (n = 5) | |||||
| Parameter | Baseline | D30 | D90 | Baseline | D30 | D90 |
| BODE (D.U.) | 8 (6 to 9) | 4 (2 to 9) | 5 (3 to 9) | 8 (6 to 9) | 5 (4/7) | 3 (1/6)a |
| MMRC (D.U.) | 4.0 (3 to 4) | 2.0 (1 to 4) | 2.0 (1 to 4) | 4.0 (3 to 4) | 2.0 (2/3)a | 1.0 (1/2)a, b |
| 6 MWT (mt) | 356 (225 to 435) | 394 (387 to 432) | 403 (356 to 429) | 182 (162 to 285) | 327 (164/332) | 351 (270/375) |
| ΔTLVR (ml) | — | −663 (−1,510 to −176) | −540 (−1,510 to −147) | — | −686 (−1,840/−171) | −998 (−3,284/−57) |
| EBV group (n = 5) | EBV + MSC group (n = 5) | |||
|---|---|---|---|---|
| Baseline | D90 | Baseline | D90 | |
| SGRQS (D.U.) | 57 (31 to 85) | 34 (22 to 93) | 73 (38 to 97) | 35 (14 to 35)a |
| SGRQA (D.U.) | 92.49 (79.7 to 93.4) | 66.29 (23.3 to 99.9) | 99.9 (61.3 to 99.9) | 60.5 (12.2 to 79.1)a |
| SGRQI (D.U.) | 63.3 (54.5 to 74.4) | 35.9 (11.2 to 74.0) | 58.4 (32.9 to 88.8) | 14.0 (9.2 to 41.5)a |
| SGRQT (D.U.) | 68.8 (61.5 to 81.9) | 44.9 (18.8 to 85.1) | 67.7 (48.3 to 93.6) | 29.9 (14.6 to 48.6)a |
Data are presented as median (range).
a
Significantly different from baseline (p < .05).
b
Significantly different from D30 (p < .05).
Abbreviations: 6MWT, 6‐minute walk test; BODE, Body mass index, airway Obstruction, Dyspnea, and Exercise index; DU, dimensionless unit; EBV, endobronchial valve; MMRC, Modified Medical Research Council dyspnea scale; MSC, mesenchymal stromal cells; MWT, Minutes Walk Test; SGRQ, Saint George Respiratory Questionnaires; TLVR, total lung volume reduction.