Figure 3.

Model of tissue resident T cells induction by various vaccination routes. The majority of vector and insert specific tissue resident T cells will reside close to the site of immunization, in the tissue where the antigen was first encountered. Some of these resident T cells migrate away from the injection site while remaining within the same tissue. Depending on the immunization routes, the generated tissue resident T cells will reside in different tissues. Of note, circulating T cells are not depicted.