Table 2.
Diseases With Potential Poly I:C dsRNA Treatment
| Disease | Delivery Method | Model | Reference |
|---|---|---|---|
| Brain Tumors | Poly-ICLC; intramuscular | Human | 22 |
| Cancer | Vaccine containing poly I:C | Human | 23 |
| Cancers | Poly ICLC + IL-2 injections | Human | 24 |
| Cerebral Ischaemia/reperfusion injury | Naked; Intraperitoneal and intravascular injection | Mouse | 25 |
| Gastric Adenocarcinoma | Liposomes; Subcutaneous | Mouse | 26 |
| Glioblastoma | Poly-ICLC; intramuscular | Human | 27 |
| Hepatitis B | Naked; hydrodynamic injection | Mouse | 28 |
| Herpes Zoster in children with cancer | Topical Poly I:C | Human | 29 |
| Influenza A Virus | Naked; Intranasal | Mouse | 30 |
| Influenza A/Puerto Rico/8/34 virus | Naked; intramuscular and intranasal | Mouse | 31 |
| Laser induced Skin Wounds | Topical Poly I:C | Human and mouse | 32 |
| Leukemia (solid tumors) | Poly ICLC injection | Human | 33 |
| Severe Acute Respiratory Syndrome | Naked; Intranasal | Mouse | 34 |