Table II.

Differences in parameters between healthy control and PIH groups. Significant differences in FBG, FINS, HOMA-IR, HOMA-ISI and HOMA-β% were observed.

Parameter	Control group (n=50)	PIH group (n=50)	P-value
FBG (pmol/l)	45.3±8.6	85.9±8.2	<0.001
FINS (mmol/l)	8.23±1.92	15.78±1.35	0.022
HOMA-IR	1.63±0.58	4.34±0.76	0.014
HOMA-β%	225.49±19.02	136.58±25.42	<0.001
HOMA- ISI	−0.25±0.02	−1.49±0.13	<0.001
TG (mmol/l)	2.12±0.72	3.35±1.43	0.035
TC (mmol/l)	5.89±1.35	5.96±1.02	0.896
LDL (mmol/l)	2.09±0.52	3.02±0.42	0.014
HDL (mmol/l)	2.55±0.32	1.94±0.25	0.028
apoB (pmol/l)	1.01±0.04	1.18±0.06	0.041
apoA-1 (pmol/l)	2.69±0.12	2.01±0.11	0.036
Urine protein (g/24 h)	0.12±0.24	1.36±0.42	0.002
BUN (mmol/l)	5.10±1.03	7.73±1.15	0.039
Scr (µmol/l)	102.32±10.51	159.15±17.32	0.008
Ccr (ml/min)	90.23±12.32	55.33±8.36	0.004

Values are expressed as the mean ± standard deviation. TG, triglyceride; TC, total cholesterol; LDL, low-density lipoprotein; HDL, high-density lipoprotein; FBG, fasting blood glucose; FINS, fasting insulin; BUN, blood urea nitrogen; Scr, serum creatinine; apo, apolipoprotein; HOMA-IR homeostasis model assessment of IR; HOMA-ISI, HOMA of insulin sensitivity index; HOMA-β%, HOMA of β-cell function; Scr, serum creatinine; Ccr, creatinine clearance rate.