Table III.
Effect of apigenin on the efflux of [3H] cholesterol in macrophages and the ratio of cholesteryl ester/TC.
| Groups | Dose (mol/l) | Cholesterol efflux rate (%) | TC (mg/g) | Cholesteryl ester (mg/g) | Cholesteryl ester/TC (%) |
|---|---|---|---|---|---|
| Control | – | 8.76±1.34 | 11.58±1.03 | 4.08±0.76 | 32.56±2.34 |
| Model | – | 7.58±1.43 | 30.58±1.58 | 15.46±0.65 | 60.45±5.54 |
| High-dose apigenin | 3×10−5 | 14.58±1.76b | 18.96±1.67b | 8.04±1.45 | 43.67±5.67 |
| Moderate-dose apigenin | 3×10−6 | 11.23±1.34a | 22.34±1.56a | 10.76±0.54a | 50.87±3.45a |
| Low-dose apigenin | 3×10−7 | 10.67±1.23 | 29.67±1.08 | 13.45±0.87b | 51.23±5.67b |
a
Based on a comparison with the control group, P<0.05
b
based on a comparison with the control group, P<0.01. TC, total cholesterol.