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Expression of Foxp3 in CD4+ T lymphocytes. Spleen cells were incubated with APC-conjugated anti-CD4 and PE-conjugated anti-Foxp3 antibodies and analyzed by flow cytometry. (A) Foxp3 isotype control; (B) normal control group; (C) collagen-induced arthritis model group; (D) 5 mg/kg/day artesunate group; (E) 10 mg/kg/day artesunate group; (F) 20 mg/kg/day artesunate group. Foxp3, forkhead/winged helix transcription factor; APC, allophycocyanin; PE, phycoerythrin.
