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Expression of Foxp3/IL-17 in CD4+ T lymphocytes.
| Group | Foxp3 (%) | IL-17 (%) |
|---|---|---|
| Normal | 1.171±0.191a | 0.514±0.352 |
| CIA model | 0.529±0.138a,b | 1.471±0.180a,b |
| Artesunate (mg/kg/day) | ||
| 5 | 0.729±0.095a | 1.257±0.134a,b |
| 10 | 1.342±0.217a,b | 0.829±0.040a,b |
| 20 | 1.671±0.123b | 0.600±0.038 |
P<0.01 vs. the 20 mg/kg/day artesunate group
P<0.01 vs. the normal group. Foxp3, forkhead/winged helix transcription factor; IL, interleukin; CIA, collagen-induced arthritis.
