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. 2017 Mar 28;13(5):2293–2303. doi: 10.3892/etm.2017.4270

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Ultrasonic analysis of microbubble-specific targeting to human umbilical cord veins. (A) Representative images of CMBs and TCMBs attached to human umbilical cord veins following TNF-α stimulation. The red dashed lines delineate the intima of the umbilical vein. A greater number of TCMBs attached to the intima of the human umbilical vein that was activated by TNF-α. (B) Acoustic intensity of the TCMBs and CMBs adhered to the umbilical vein endothelium was 25.6±7.3 and 8.2±2.6 dB, respectively. CMB, non-targeted cationic microbubble; TCMB, targeted cationic microbubble; TNF, tumor necrosis factor.