Figure 1.
Mean ± standard error of the mean for (a) glucose, (b) hemoglobin A1c, and (c) C-peptide levels at baseline (black bars) and after 1 year (white bars) and ∼5 years (gray bars) of metreleptin treatment. Normal ranges are indicated by dashed lines (glucose, 70–100 mg/dL; hemoglobin A1c, 4%–5.7%; C-peptide, 0.5–3 mg/dL). *Statistically significant changes relative to baseline.