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. 2017 Jan 23;102(5):1511–1519. doi: 10.1210/jc.2016-3628

Figure 2.

Figure 2.

Mean ± standard error of the mean of lipid levels (geometric mean and 95% confidence intervals for triglyceride levels) at baseline (black bars) and after 1 year (white bars) and ~5 years (gray bars) of metreleptin treatment. (a) Triglyceride, (b) total cholesterol, (c) HDL, and (d) LDL levels. Upper limits for low cardiovascular risk in children for levels of triglycerides (150 mg/dL), total cholesterol (170 mg/dL), and LDL (110 mg/dL), and the lower limit for low cardiovascular risk for HDL level (35 mg/dL) are indicated by dashed lines. *, statistically significant changes relative to baseline.