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. 2017 Jun 7;5:2765. Originally published 2016 Nov 25. [Version 2] doi: 10.12688/f1000research.8937.2

Table 5. Life Table of egg survival and probabilities during the first two weeks of development derived solely from Hertig’s data.

The table is modelled on Leridon’s life table 26 and includes his values for survivors and data from Hertig 5. Probabilities are also shown for each stage of the early development process. Medians and 95% confidence intervals derived from a bootstrap analysis of Hertig’s data indicate the precision in the estimates for fertilisation and embryo loss in the first two weeks. *Although Leridon’s values are based on Hertig, they do not fully match. Leridon reports losses of 15 and 27 in the first and second weeks respectively. However, Hertig’s 60% loss of abnormal pre-implantation embryos implies 25 (0.6 × 42) losses in the first week leaving 58, and 16 (58 × (6/21)) losses in the second week, leaving 42. ¥A value of π SOC = 0.90 was used to avoid the calculation of probabilities greater than 1.

Week after Ovulation Biological Description Survivors (Leridon 26) Survivors (Hertig 5) Bootstrap Median
[95% CIs]
Number of Cycles 100 100 100 [100, 100]
0 Fertilised Eggs 84 83 84 [39, 227]
1 Implanted Embryos 69* 58 58 [41, 74]
2 Missed First Period 42 42 42 [26, 59]
Probabilities Biological Description Probabilities Probabilities Bootstrap Median
[95% CIs]
π SOC × π FERT Fertilisation per cycle 0.84 0.83 0.84 [0.39, 2.27]
π FERT (when π SOC = 0.90 ¥) Fertilisation per ideal insemination 0.93 0.93 0.93 [0.43, 2.52]
π HCG Fertilised egg implanting 0.82* 0.70 0.69 [0.27, 1.28]
π CLIN Implanted egg to clinical recognition 0.61* 0.71 0.71 [0.50, 0.91]
π HCG × π CLIN Fertilised egg to clinical recognition 0.50 0.50 0.50 [0.20, 0.88]