Fig 3. Enrichment analyses of shared co-expressed partners between 14 known obesity-related genes and the candidate genes from this study.

A: Key players on the regulation of food intake and energy expenditure mostly act through the leptin-melanocortin pathway. B: Shared co-expressed partners between the four candidate genes (GRIK1, GRM7, GRPR, SLCO4C1) and 500 randomly generated gene sets. The number shared co-expressed partners of the candidate genes with the 14 obesity-related genes are indicated by a red arrow. C: Co-expression network including the selected obesity-related genes and GRIK1, GRM7, GRPR, SLCO4C1. This network was visualized using Cytoscape.