Table 2. SAR of Positions 5′ and 6′ for BRPF2 BD, BRPF1 BD, TAF1 BD2, and BRD4 BD1 Activity.
a
Determined using a TR-FRET assay.
b
All compounds show an IC50 > 20000 nM for BRD4 BD2.
C
Compounds are racemates.
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