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. 2017 May 24;7:2314. doi: 10.1038/s41598-017-01027-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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miRNA-29c promotes inflammatory cytokines synthesis. (A) ELISA analysis showed the expression of inflammatory cytokines in podocytes transfected with mimics (30 nM) or inhibitors (100 nM) for 48 h. (B) qRT-PCR analysis of in-flammatory cytokines expression in podocytes transfected with mimics or inhibitors. (C) ELISA analysis showed the expression of inflammatory cytokines in podocytes were transfected with miRNA-29c inhibitor (100 nM) and treated with HG (25 mM) for 48 h as compared with NG. (D) qRT-PCR analysis of inflammatory cytokines mRNA expression in podocytes transfected with miRNA-29c inhibitors (100 nM) and treated with HG (25 mM) for 24 h. Results were obtained from three independent experiments. Data are shown as mean ± SEM. *P < 0.05 compared with control. ^# P < 0.05 compared with high glucose group.