Skip to main content
. 2017 May 24;7:2360. doi: 10.1038/s41598-017-02546-x

Figure 5.

Figure 5

Effect of colonic administration of SCFA mixtures on fasting and postprandial plasma inflammatory cytokines (A) Fasting (t0–t120 min) and postprandial (t180–t300 min) plasma IL-1β concentrations after colonic SCFA infusions. (B) iAUC for fasting (t0–t120 min) plasma IL-1β following colonic SCFA infusion. Values are means ± SEMs (n = 10, for two volunteers IL-1β concentrations were not detectable). Overall treatment effect for fasting IL-1β P = 0.068 (period P = 0.626, carry-over P = 0.841). (C) Fasting (t0–t120 min) and postprandial (t180–t300 min) plasma TNF-α after colonic SCFA infusions. Values are means ± SEMs (n = 12).) (D) Fasting (t0–t120 min) and postprandial (t180–t300 min) plasma IL-6 after colonic SCFA infusions. Values are means ± SEMs (n = 11, for one participant IL-6 concentrations were not detectable). (E) Fasting (t0–t120 min) and postprandial (t180–t300 min) plasma IL-8 after colonic SCFA infusions. Values are means ± SEMs (n = 12). Statistical significance indicated as asterisk (*) when *P < 0.05 and as hashtag when # P < 0.10.