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. 2017 May 24;7:2329. doi: 10.1038/s41598-017-02407-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Atorvastatin increases the phagocytic function of ARPE-19 cells in a dose-dependent manner. (a) Count of phagocytic cells (Y axis), represented by number of FITC-positive cells, and fluorescence intensity (X axis), as determined by flow cytometry of ARPE-19 cells incubated with fluorescein-labeled carboxylate microspheres and treated with different concentrations of atorvastatin. (b) Quantification of the percentage of phagocytic cells shown in (a). (c) Quantification of the fold change of phagocytic index (or mean fluorescence intensity). The results are expressed as mean ± SE. *p < 0.05 versus control group.