This study demonstrated that antibodies against the infliximab biosimilar CT-P13 and the infliximab reference product (RP; Remicade) recognise and bind RP and CT-P13, respectively. |
The cross-reactivity of CT-P13 and its RP indicate that the two products share immunodominant epitopes. |
The findings of this study are consistent with the previously reported high biosimilarity of CT-P13 to its RP and suggest that commercialised kits for the detection of antidrug antibodies against infliximab can be utilised for either CT-P13 or its RP. |