Table 2.

Association between LRRC16A SNPs and Survival of Patients with Acute Respiratory Distress Syndrome

	Survival28d*		Survival60d†
SNP‡	HR (95% CI)	P Value (FDR-q)	HR (95% CI)	P Value (FDR-q)
rs9358856	0.57 (0.38–0.87)	0.0084 (0.04)	0.55 (0.38–0.81)	0.0020 (0.01)
rs2274089	0.63 (0.38–1.04)	0.0714 (0.12)	0.69 (0.42–1.11)	0.1260 (0.25)
rs7766874	0.80 (0.63–1.01)	0.0610 (0.12)	0.85 (0.68–1.06)	0.1528 (0.25)
rs1012899	1.12 (0.82–1.52)	0.4762 (0.48)	1.10 (0.81–1.50)	0.5344 (0.67)
rs742132	1.12 (0.87–1.45)	0.3684 (0.46)	1.05 (0.82–1.36)	0.6816 (0.68)

Definition of abbreviations: CI = confidence interval; FDR-q = false discovery rate–adjusted P value; HR = hazard ratio per minor/effect allele; LRRC16A = leucine-rich repeat–containing 16A; SNP = single-nucleotide polymorphism.

The model was adjusted for age, sex, blood transfusion, baseline platelet count, and Acute Physiology and Chronic Health Evaluation III score.

^*Primary outcome.

^†Secondary outcome.

^‡Analyzed in additive genetic model.