Figure 1.

Microdissection and miRNA Microarray Analysis of dMMR and pMMR Colon Cancer Cells

(A) dMMR and pMMR colon cancer cells were captured from fixed tissue-sections by laser capture microdissection. (B) Principal-component analysis shows the dMMR and pMMR cells were distinctly clustered. (C) Unsupervised hierarchical clustering analysis of the 12 miRNAs differentially expressed between the dMMR and pMMR colon cancer cells. Higher intensities of red indicate higher expression levels, while lower intensities of green indicate lower expression levels.