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Plots showing p53TAD binding to fragments of MdmX with and without the flexible linker and WW motif. Black circles show enthalpy per mole of injectant, measured using isothermal titration calorimetry, plotted as a function [p53TAD]/[MdmX]. Black lines show the fit to the data using a single site binding model. (a) Shown here is p53TAD binding to MdmX23–111. (b) Shown here is p53TAD binding to MdmX23–210.
