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. 2017 Mar 29;6(6):512–523. doi: 10.1016/j.molmet.2017.03.008

Figure 1.

Figure 1

Effect of nighttime restricted feeding on metabolic responses of WT and MT to HFD. A, B: Body weight development (A) and weekly weight gain (B) of WT and MT mice under ad libitum or nighttime-restricted (RF) access to HFD. C, D: Cumulative (C) and daily food intake (D) of ad libitum and nighttime-fed WT and MT mice. E, F: Daily activity (E) and energy expenditure (EE) (F) of ad libitum and nighttime-fed WT and MT mice. Data are shown as means ± SEM (n = 12 per group); 2-way ANOVA with Bonferroni post-test; *: p < 0.05; **: p < 0.01; ***/###: p < 0.001. L – light phase; D – dark phase. Different letters (a, b, …) depict statistically significant differences (p < 0.05).