TABLE 1.
Demographics of patients with S. aureus and Gram-negative bloodstream infections at Duke University Medical Center from 2002 to 2015
| Parameter | No. (%) of patients |
Pa | |
|---|---|---|---|
| S. aureus (n = 999) | Gram negative (n = 1,660) | ||
| Mean age (yrs) | 57.7 | 61.1 | <0.0001 |
| Race/ethnicity | |||
| White | 597 (60) | 1,105 (67) | <0.0001 |
| Black | 377 (38) | 474 (29) | |
| Hispanic | 3 (<1) | 10 (1) | |
| Native American | 9 (1) | 12 (1) | |
| Asian | 4 (<1) | 23 (1) | |
| Other/unknown | 9 (1) | 36 (2) | |
| Female | 446 (45) | 752 (45) | 0.75 |
| Medical history | |||
| Recent glucocorticoid use | 222 (22) | 409 (25) | 0.16 |
| Neoplasm | 210 (21) | 639 (38) | <0.0001 |
| Diabetes mellitus | 418 (42) | 568 (34) | <0.0001 |
| Transplant | 84 (8) | 226 (14) | <0.0001 |
| Surgery in past 30 days | 272 (27) | 432 (26) | 0.50 |
| Hemodialysis dependence | 214 (21) | 160 (10) | <0.0001 |
| Rheumatologic disorder | 30 (3) | 39 (2) | 0.32 |
| Site of acquisition | |||
| Community acquired | 746 (75) | 1,147 (69) | 0.002 |
| Hospital acquired | 241 (24) | 513 (31) | |
| Source of infection | |||
| Pneumonia | 100 (10) | 122 (7) | <0.0001 |
| Urine/pyelonephritis | 5 (1) | 522 (31) | |
| Abscess | 38 (4) | 80 (5) | |
| Line associated | 263 (26) | 187 (11) | |
| Skin/soft tissue | 164 (16) | 95 (6) | |
| Biliary tract | 4 (<1) | 95 (6) | |
| Other | 185 (19) | 193 (12) | |
| Source not identified | 240 (24) | 366 (22) | |
| Mean APACHE-II score | 15.3 | 14.8 | 0.04 |
| Mean chronic APACHE-II score | 3.9 | 3.6 | 0.31 |
a
Statistically significant values are indicated in boldface.