TABLE 1.
Strain | MIC (μg/ml) ofa: |
AMRb gene(s) | Plasmid(s) (kb) | mcr-1 plasmids (kb) | blaCTX-M plasmid (kb) | CIc form | |||||
---|---|---|---|---|---|---|---|---|---|---|---|
CLS | AMK | CTX | CIP | CRO | FOS | ||||||
14 | 8 | 4 | 8 | 0.12 | >16 | >512 | blaCTX-M-14, fosA3 | ∼104, ∼230 | ∼230, IncHI2 | ∼230 | + |
TC14 | 4 | 0.5 | 8 | 0.06 | >16 | <4 | blaCTX-M-14 | ∼230 | ∼230, IncHI2 | ∼230 | + |
25 | 8 | 2 | >16 | >16 | >16 | >512 | blaCTX-M-55, fosA3 | ∼33, ∼60, ∼104 | ∼33, IncX4 | ∼60 | − |
TC25 | 4 | 1 | 4 | 0.015 | >16 | <4 | blaCTX-M-55 | ∼33, ∼60 | ∼33, IncX4 | ∼60 | − |
149 | 8 | >128 | >16 | >16 | >16 | >512 | blaCTX-M-55, fosA3 | ∼33, ∼60, ∼90 | ∼33, IncX4 | ∼60 | − |
TC149 | 8 | 0.5 | >16 | 0.015 | >16 | <4 | blaCTX-M-55 | ∼33, ∼60 | ∼33, IncX4 | ∼60 | − |
163 | 8 | 4 | >16 | >16 | >16 | >512 | blaCTX-M-55, blaCTX-M-65, fosA3 | ∼60, ∼78, ∼104, ∼138 | ∼60, IncI2 | ∼60 | − |
TC163 | 8 | 0.5 | >16 | 0.015 | >16 | <4 | blaCTX-M-55 | ∼60 | ∼60, IncI2 | ∼60 | − |
199 | 8 | 1 | >16 | 0.5 | >16 | <4 | blaCTX-M-14 | ∼90, ∼120, ∼280 | ∼280, IncHI2 | ∼280 | + |
TC199 | 8 | 0.5 | >16 | 0.015 | >16 | <4 | blaCTX-M-14 | ∼280 | ∼280, IncHI2 | ∼280 | + |
328 | 4 | 2 | >16 | 2 | >16 | >512 | blaCTX-M-55, fosA3 | ∼33, ∼90 | ∼33, IncX4 | ∼90 | − |
TC328 | 4 | 0.5 | >16 | 0.0075 | >16 | <4 | blaCTX-M-55 | ∼33, ∼90 | ∼33, IncX4 | ∼90 | − |
383 | 8 | 4 | >16 | >16 | >16 | >512 | blaCTX-M-55, fosA3 | ∼33, ∼60, ∼78, ∼138, ∼200 | ∼33, IncX4 | ∼60 | − |
TC383 | 4 | 0.5 | >16 | 0.0075 | >16 | <4 | blaCTX-M-55 | ∼33, ∼60 | ∼33, IncX4 | ∼60 | − |
384 | 4 | >128 | >16 | >16 | >16 | >512 | blaCTX-M-55, fosA3 | ∼60, ∼120 | ∼60, IncI2 | ∼60 | − |
TC384 | 2 | 0.5 | >16 | 0.0075 | >16 | <4 | blaCTX-M-55 | ∼60 | ∼60, IncI2 | ∼60 | − |
391 | 4 | 2 | >16 | 0.5 | >16 | <4 | blaCTX-M-14 | ∼33, ∼104, ∼250 | ∼250, IncHI2 | ∼250 | + |
TC391 | 4 | 0.5 | 4 | 0.015 | >16 | <4 | blaCTX-M-14 | ∼250 | ∼250, IncHI2 | ∼250 | + |
J53 | 1 | 0.03 | 0.015 | 0.5 | 1 | <4 | − | − | − | − | − |
CLS, colistin; AMK, amikacin; CTX, cefotaxime; CIP, ciprofloxacin; CRO, ceftriaxone; FOS, fosfomycin.
AMR, antimicrobial resistance.
CI, circular intermediate.
−, negative; +, positive.