FIG 6.
In vitro inhibition (in percent) of Fe-SOD from L. infantum (A and B) and L. braziliensis (C and D) promastigote forms by the Se derivatives. The differences between the activities of the control homogenate and homogenates incubated with the indicated compounds were obtained according to the Newman-Keuls test. The concentrations in the keys are IC50s, which are the concentrations required to give 50% inhibition and which were calculated by linear regression analysis from the values of the equilibrium constants (Kc) at the concentrations employed (0.5 to 100 μM). The values are averages from three different determinations.