Table 2.

Regions in which neural recruitment was related to age

ROI	Hemisphere	BA	MNI coordinates
			x	y	z	t-value	k
Positive effect of age on neural recruitment during search
Frontal lobe
Dorsal prefrontal cortex	L	8	−34	24	40	4.36	551
	R	8	22	30	48	2.97	42
Premotor cortex	L	6	−10	−10	62	4.29	1204
Precentral gyrus	R	4	28	−14	58	3.56	237
Lateral prefrontal cortex	L	46	−36	38	14	3.50	89
	R	6	60	0	38	3.24	70
	R	6	60	4	14	2.99	64
Ventrolateral prefrontal cortex	L	47	−34	32	−10	2.92	36
Temporal lobe
Middle temporal gyrus	L	39	−40	−60	30	4.32	308
	L	21	−66	−38	−6	3.21	43
Fusiform gyrus	R	20	60	−30	−34	3.08	29
Parietal lobe
Supramarginal gyrus	L	40	−58	−36	36	3.22	58
Inferior parietal lobule	L	40	−58	−44	46	3.16	66
	R	40	62	−32	46	2.84	53
Precuneus	L	7	−10	−52	64	3.04	37
Postcentral gyrus	R	40	60	−24	22	2.89	52
Other
Anterior cingulate	L	32	0	46	−12	4.26	858
Posterior cingulate	L	31	−6	−56	28	3.49	100
Insula	L	13	−58	−34	18	3.19	53
Negative effect of age on neural recruitment during search
Frontal lobe
Premotor cortex	L	6	−50	4	54	5.49	721
	L	6	0	14	52	3.75	186
	L	6	−36	0	28	3.31	34
Lateral prefrontal cortex	R	9	56	28	26	4.05	300
Dorsomedial prefrontal cortex	R	8	4	38	36	3.50	65
Temporal lobe
Fusiform gyrus	L	37	−32	−52	−18	6.11	2670
	R	20	38	−42	−20	3.61	331
Parietal lobe
Precuneus	L	7	−24	−58	42	4.11	363
	R	7	30	−62	44	3.59	237
	L	7	−24	−70	60	3.05	34
Occipital lobe
Lingual gyrus	R	19	22	−70	−6	3.65	159
Other
Posterior cingulate	L	23	0	−30	22	5.54	598
	R	31	20	−64	30	3.52	235
Claustrum	L	NA	−30	24	0	3.36	97
Positive effect of age on neural recruitment during elaboration
Frontal lobe
Orbitofrontal cortex	L	11	−22	36	−12	3.50	61
Temporal lobe
Angular gyrus	L	39	−34	−74	40	3.79	365
Superior temporal gyrus	L	22	−58	−4	−10	3.30	132
Parietal lobe
Inferior parietal lobule	L	40	−62	−28	32	4.26	1125
Postcentral gyrus	R	2	56	−20	28	3.70	461
	L	2	−36	−32	72	3.29	71
	L	7	−20	−46	58	3.18	117
Precuneus	R	7	12	−60	74	3.68	985
Occipital lobe
Fusiform gyrus	R	19	34	−84	−10	5.27	2141
	R	19	22	−48	2	3.17	156
	L	19	−36	−64	14	2.97	55
Middle occipital gyrus	L	18	−32	−88	−6	5.15	1462
Lingual gyrus	L	17	2	−94	8	3.42	67
Other
Posterior cingulate	L	30	−14	−58	12	3.87	885
	L	31	−12	−32	48	3.76	288
	R	31	4	−46	42	2.99	61
Anterior cingulate	R	32	2	48	−6	3.02	43
Positive effect of age on neural recruitment during elaboration
Frontal lobe
Premotor cortex	L	6	−50	6	52	4.30	129
	L	6	−28	6	66	3.51	78
	R	6	16	4	66	3.13	61
Lateral prefrontal cortex	L	9	−58	14	26	3.02	32
Occipital lobe
Lingual gyrus	R	18	14	−86	−2	3.16	51

Clusters significant at an uncorrected threshold of p < 0.005, k ≥ 29 voxels.

BA, Approximate Brodmann area.