−30 |
Begin continuous physiological monitoring, pupils, subjective effects, CPT, performance battery |
0 |
Pioglitazone or Placebo |
15 |
Subjective effects, pupils, |
30 |
Subjective effects, pupils, blood, CPT |
45 |
OXY 0 mg, PO |
60 |
Subjective effects, pupils, |
75 |
Subjective effects, pupils, blood, CPT |
90 |
OXY 10 mg, PO: Subjective effects, pupils |
105 |
Subjective effects, pupils, |
120 |
Subjective effects, pupils, blood |
135 |
OXY 20 mg, PO (cumulative dose of 30 mg): Subjective effects, pupils |
150 |
Subjective effects, pupils, |
165 |
Subjective effects, pupils, blood, CPT |
180 |
Subjective effects, pupils, blood, CPT, |
195 |
Performance battery |
210 |
Subjective effects, pupils, CPT |
255 |
Subjective effects, pupils, performance battery, CPT |
315 |
Subjective effects, pupils, blood, CPT, performance battery |