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. Author manuscript; available in PMC: 2017 May 25.
Published in final edited form as: Physiol Behav. 2015 Oct 9;159:33–39. doi: 10.1016/j.physbeh.2015.10.006

Table 2. Mean Maintenance Phase Measures.

a

Results of various study measures collected during the 3 PIO maintenance periods leading to laboratory testing.

PIO 0 mg PIO 15 mg PIO 45 mg
Mean (SD) Mean (SD) Mean (SD) F Value Sig.
I Want Rx Ops (0–100) 6.4 (9.7) 3.9 (8.6) 4.2 (9.3) 1.4 0.9
I Want Marijuana 12.8 (28.2) 12.3 (21.1) 9.4 (15.9) 1.1 0.85
I Want Alcohol 5.1 (24.4) 4.5 (12.5) 3.3 (10.3) 0.79 0.78
I Want Tobacco 11.9 (27.8) 13.4 (23.0) 9.5 (16.9) 0.66 0.74
# of Opioid + UTox b 0.71 (0.88) 1.1 (0.5) 1.3 (0.8) 0.74 0.47
# of Cocaine + UTox b 2.0 (1.9) 3.6 (2.2) 3.8 (1.9) 0.32 0.22
Plasma PIO c (ng/ml) 0.0 (0.0) 514 (257) 1155 (514) 9.65 0.001
a

Only positive samples for cocaine, opioids, oxycodone and THC were found. THC is unreported because the drug’s persistence in urine samples significantly confounds estimating separate positive samples.

b

Mean taken only from those participants who tested positive.

c

Obtained during the lab session following each maintenance/stabilization phase.