Table 3.
Predictors (Bivariate Analysis)
| Abstinence-Induced Withdrawal (n=19) | Naloxone-Precipitated Withdrawal (n=29) | |||
|---|---|---|---|---|
|
| ||||
| R (p-value) | B (95% CI) | R (p-value) | B (95% CI) | |
| Age | -- | -- | −0.29 (0.13) | −1.41 [−3.23–0.42] |
| Years of Heroin Use | -- | -- | −0.41 (0.03) | −1.54 [−2.88–−0.19] |
| Cocaine Use (Yes/No) | -- | -- | −0.39 (0.04) | −29.0[−56.1–−1.98] |
| Years of Cocaine Use | 0.95 (0.20) | 1.43 [−4.56–7.41] | -- | -- |
| Nicotine Use (Yes/No) | 0.59 (0.01) | 13.1 [3.94–22.3] | -- | -- |
| Cigarettes per Day | -- | -- | −0.51 (0.01) | −3.92 [−6.50– −1.31] |
| Rx Opioid Use (Yes/No) | 0.07 (0.14) | 4.94 [−1.84–11.7] | 0.35 (0.06) | 27.4 [−1.34–56.2] |
| Rx Opioid Use (Route of Administration) | -- | -- | −0.61 (0.06) | −12.3[−36.1–11.5] |
| Bup Use (Yes/No) | -- | -- | 0.35 (0.07) | 14.5 [−2.00–57.3] |
| Bup Use (Frequency) | −0.95 (0.01) | −13.5 [−21.7– −5.25] | −0.50 (0.17) | −7.13 [−22.3–8.05] |
| Bup Use (Dose per Occasion) | -- | -- | −0.59 (0.09) | −4.78 [−13.4–3.82] |
| Last Use of Heroin (hrs) | -- | -- | −0.34 (0.08) | −6.12 [−12.84–.60] |
| OPRM1: rs6848893 | 0.45 (0.06) | 5.21 [−0.29–10.7] | -- | -- |
| OPRD1: rs10753331 | 0.03 (0.07) | 4.64 [−0.39–9.68] | -- | -- |
| OPRD1: rs678849 | 0.08 (0.16) | −3.38 [−8.23–1.48] | -- | -- |
| OPRK1: rs963549 | -- | -- | −0.23 (0.22) | −13.5 [−35.8–8.8] |