Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 21;16(9):852–860. doi: 10.1080/15384101.2017.1304329

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Taylor & Francis

PMC Copyright notice

Figure 1. — Elmod2 is an oocyte-prominent protein and primary GAP in mouse ovaries. (A) RT-PCR showed Elmod2 was the most abundant among all Elmo and Elmod family members in mouse oocytes. (B) Immunoblotting in ovaries at different post-natal day (PND) showed that protein level of Elmod2 significantly increased at PND3 and peaked at PND21. (C) Elmod2 was much more predominant in oocytes than in theca cells (TCs) and cumulus cells (CCs). (D) Immunoblotting showed that Elmod2 was constant from GV to MII stage. (E) Immunofluorescence in mouse oocytes showed that Elmod2 (green) was rich in nucleus of GV oocytes and concentrated within spindles regions during meiosis. DAPI in blue. (F) Immunofluorescence of oocyte at MI stage showed the co-localization of Elmod2 (green) and γ-tubulin (purple) on spindle poles. Scale bars, 20 μm.