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. Author manuscript; available in PMC: 2017 May 25.
Published in final edited form as: J Immunol. 2009 Sep 14;183(7):4809–4816. doi: 10.4049/jimmunol.0901616

FIGURE 3.

FIGURE 3

sIAg7-GADp217 vaccination induces active immunoregulation. NOD.scid mice received 5 × 106 splenocytes from diabetic (n = 11) or nondiabetic sIAg7-GADp217 treated (n = 6) NOD female mice alone, or a mixture of an equal number of splenocytes (5 × 106) from diabetic NOD plus sIAg7-GADp217 (n = 7) or sIAg7-HEL (n = 5) dimer treated NOD donors, and diabetes was monitored. *, p = 0.0005, by Kaplan-Meier log-rank test, for diabetogenic splenocytes alone vs sIAg7-GADp217 splenocytes alone and †, p ≤ 0.0015, for diabetogenic splenocytes alone or a mixture of diabetogenic plus sIAg7-HEL splenocytes vs a mixture of diabetogenic plus sIAg7-GADp217 splenocytes.