Skip to main content
. Author manuscript; available in PMC: 2017 May 25.
Published in final edited form as: Brain. 2002 Jul;125(Pt 7):1450–1461. doi: 10.1093/brain/awf151

Fig. 1.

Fig. 1

Histopathology of NMO. (A) Spinal cord cross-section demonstrating extensive demyelination involving both the grey and white matter (Luxol fast blue and PAS myelin stain, mag × 10). (B) The lesion is filled with numerous macrophages (KiM1P pan-macrophage stain). (C) There is a sharp demarcation between the periplaque white matter and the plaque edge (Luxol fast blue and PAS myelin, mag × 100). (D) Macrophages within the actively demyelinated lesion contain myelin debris within the cytoplasm (arrow; immunocytochemistry for MOG, mag × 600).