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. 2017 May 25;13(5):e1006756. doi: 10.1371/journal.pgen.1006756

Table 3. Total number of deaths and standardized mortality ratios (SMR) due to respiratory, digestive and endocrine diseases by 1% increase in the Native American (HGDP), Mapuche and Aymara proportions.

ICD Description Deaths Native American (HGDP) Mapuche Aymara
Pval SMR 95% CI Pval SMR 95% CI Pval SMR 95% CI
Diseases of the respiratory system
J18 Pneumonia, unspecified organism 23265 0.001 0.984 0.975 0.994 4 10−8 1.016 1.011 1.022 10−9 0.981 0.975 0.987
J44 Other chronic obstructive pulmonary disease 18427 0.006 0.988 0.980 0.997 10−6 1.012 1.007 1.017 10−7 0.986 0.981 0.991
J45 Asthma 1383 0.14 0.981 0.957 1.006 5 10−10 1.047 1.032 1.061 10−7 0.950 0.932 0.968
J62 Pneumoconiosis due to dust containing silica 616 0.54 1.022 0.953 1.095 3 10−7 0.891 0.854 0.930 0.0002 1.064 1.031 1.099
J69 Pneumonitis due to solids and liquids 1499 0.008 0.963 0.936 0.990 0.001 1.026 1.010 1.042 8 10−5 0.962 0.944 0.980
J84 Other interstitial pulmonary diseases 7697 10−6 1.030 1.018 1.043 5 10−11 0.975 0.968 0.982 4 10−15 1.026 1.020 1.032
Diseases of the digestive system
K70 Alcoholic liver disease 10828 0.10 0.990 0.978 1.002 10−10 1.023 1.017 1.030 10−8 0.977 0.970 0.985
K74 Fibrosis and cirrhosis of liver 9957 9 10−5 1.019 1.010 1.029 10−13 0.978 0.973 0.984 10−15 1.021 1.016 1.026
K76 Other diseases of liver 5581 0.56 0.996 0.982 1.010 10−7 0.979 0.971 0.986 0.0004 1.014 1.006 1.021
Endocrine, nutritional and metabolic diseases
E14 Unspecified diabetes mellitus 12490 0.10 0.993 0.984 1.002 2 10−6 0.987 0.982 0.993 0.009 1.007 1.002 1.012
E46 Unspecified protein-calorie malnutrition 2819 0.01 1.019 1.004 1.035 0.001 0.985 0.975 0.994 9 10−5 1.017 1.008 1.025
E88 Other and unspecified metabolic disorders 276 0.07 1.058 0.996 1.124 5 10−5 0.928 0.896 0.962 4 10−5 1.058 1.030 1.087

Bold represents associated probability values under 0.0001