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. 2017 May 25;12(5):e0177839. doi: 10.1371/journal.pone.0177839

Table 6. Effect of the intervention on child morbidity1.

Child morbidity outcomes Control Intervention P-value
Reported illness in the 2 weeks before the visit
Number of observed children × year2 156 160 -
Number of children3 1073 1164
Cumulative episodes of illness (n) 632 730 -
Number of episodes per child × year (95% CI)4 4.1 (3.8, 4.4) 4.6 (4.2, 4.9) -
Incidence rate ratio (95% CI)5 reference 1.1 (1.0, 1.3) 0.024
Reported diarrhea in the 2 weeks before the visit
Number of observed children × year2 155 160
Number of children3 1068 1160
Cumulative episodes of diarrhea (n) 202 237 -
Number of episodes per child × year (95% CI)4 1.3 (1.1, 1.5) 1.5 (1.3, 1.7) -
Incidence rate ratio (95% CI)5 reference 1.1 (0.9, 1.4) 0.16
Reported fever in the 2 weeks before the visit
Number of observed children × year2 155 160
Number of children3 1068 1164
Cumulative episodes of fever, (n) 542 600 -
Number of episodes per child × year (95% CI)4 3.5 (3.2, 3.8) 3.7 (3.5, 4.0)
Incidence rate ratio (95% CI)5 reference 1.1 (0.9, 1.2) 0.15
Reported acute respiratory infection in the 2 weeks before the visit
Number of observed children × year2 156 160
Number of children3 1076 1165
Cumulative episodes of acute respiratory infection (n) 55 52
Number of episodes per child × year (95% CI)4 0.3 (0.3, 0.5) 0.3 (0.2, 0.4)
Incidence rate ratio (95% CI)5 reference 0.9 (0.6, 1.3) 0.61
Knowledge score for recognizing dangerous child health signs, mean difference, (95% CI)6 reference 3.3 (0.4, 6.4) 0.03

1 CI, confidence interval; Child morbidity results based on caregivers’ recall.

2 Calculated by the number of children followed-up × number of visits x observation duration of 2 weeks per visit, converted into years.

3 Number of children with at least one data point included in the analysis.

4 Confidence intervals are estimated from a Poisson regression model adjusted for clustering by health center catchment area.

5 Computed using a generalized linear latent and mixed model, with cluster pair and child as random effects, adjusted for child’s age and sex, and household socioeconomic score.

6 Computed using a mixed-effects linear regression model, with cluster pair and child as random effects, adjusted for women’s age, parity, education level, and household socioeconomic score.