Figure 1. Expression of EGFR, IGF-IR and CNR2 proteins in ERα- and ERα+ breast cancer cells and correlation of CNR2 to breast cancer patient prognosis.
A. Western blot image shows expression of EGFR, IGF-IR and CNR2 proteins in different ERα- (SCP2, MDA-MB231 and SUM159) and ERα+ (MCF-7 and T47D) breast cancer cell lines. GAPDH was used as a loading control. B. Kaplan Meier blot showing recurrence free survival (RFS) of high/low expressing CNR2 breast cancer patients of ERα- subtype. P value = ~ zero. C. Kaplan Meier blot showing recurrence free survival (RFS) of high/low expressing CNR2 breast cancer patients of ERα+ subtype. P value = 1e−05.