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. 2017 Feb 22;8(18):30175–30189. doi: 10.18632/oncotarget.15621

Table 1. Distribution of PD-L1+ specimens using different scoring criteria (N=428).

Criteria for positivity Percentage of PD-L1+ Specimens
Tumor cells ≥1%* Tumor cells ≥5%@ Tumor cells ≥25%# Stromal cells ≥1% Immune cells ≥1% All cell Types ≥1%
PD-L1+ 341(79.67) 140(32.71) 39(9.11) 245(57.24) 57(13.32) 407(95.09)
PD-L1- 87(20.32) 288(67.29) 389(90.89) 183(42.76) 371(86.68) 21(4.91)

* Primary criteria used in this study: ≥1% expression on tumor cell membranes with ≥1+ intensity;

@ ≥5% expression on tumor cell membranes with ≥1+ intensity;

#≥25% expression on tumor cell membranes with ≥2+ intensity.