Table 1. Distribution of PD-L1+ specimens using different scoring criteria (N=428).
Criteria for positivity | Percentage of PD-L1+ Specimens | |||||
---|---|---|---|---|---|---|
Tumor cells ≥1%* | Tumor cells ≥5%@ | Tumor cells ≥25%# | Stromal cells ≥1% | Immune cells ≥1% | All cell Types ≥1% | |
PD-L1+ | 341(79.67) | 140(32.71) | 39(9.11) | 245(57.24) | 57(13.32) | 407(95.09) |
PD-L1- | 87(20.32) | 288(67.29) | 389(90.89) | 183(42.76) | 371(86.68) | 21(4.91) |
* Primary criteria used in this study: ≥1% expression on tumor cell membranes with ≥1+ intensity;
@ ≥5% expression on tumor cell membranes with ≥1+ intensity;
#≥25% expression on tumor cell membranes with ≥2+ intensity.