Table 2. PD-L1 expression and TIL density.
| TIL density score | Patients by PD-L1 expression status*, n (%) | ||
|---|---|---|---|
| Total (n=428) | PD-L1+(n=341) | PD-L1− (n=87) | |
| None (0)@ | 27 (6.3) | 14 (51.9) | 13 (48.1) |
| Rare (1) | 131 (30.6) | 95 (72.5) | 36 (27.5) |
| Moderate (2) | 198 (46.3) | 174 (87.9) | 24 (12.1) |
| High (3) | 72 (18.8) | 58 (80.6) | 14 (19.4) |
*≥1% of tumor cell membranes with ≥1+ intensity were considered PD-L1+; non-zero correlation, p=0.0019.
@ The amount of TILs was evaluated from the H&E stained specimens and assigned a semiquantitative score from 0 to 3, with 0=none, 1=rare, 2=moderate and focal infiltration of tumor, and 3=prominent and diffuse infiltration amongst tumor.