Table 3. Clinicopathologic features of the ESCC patients.
| Clinicopathologic parameter | No. of patients (%) | |||
|---|---|---|---|---|
| Total | PD-L1- | PD-L1+ | P@ | |
| Total | 428 | 87(20.3) | 341(79.7) | |
| Age(years) | ||||
| ≤60 | 181(42.3) | 39(44.8) | 142(41.6) | 0.591 |
| >60 | 247(57.7) | 48(55.2) | 199(58.4) | |
| Gender | ||||
| Female | 93(21.7%) | 19(21.8) | 74(21.7) | 0.978 |
| Male | 335 (78.3%) | 68(78.2) | 267(78.3) | |
| Level of differentiation | ||||
| Moderate to high | 257(60.0) | 44(50.6) | 213(62.5) | 0.122 |
| Low | 142(33.2) | 35(40.2) | 107(31.4) | |
| Others* | 29(6.8) | 8(9.2) | 21(6.2) | |
| Primary tumor location# | ||||
| Upper thoracic | 108(26.9) | 17(20.2) | 91(28.7) | 0.120 |
| Middle and lower thoracic | 293(73.1) | 67(79.8) | 226(71.3) | |
| Tumor invasion depth (T) # | ||||
| T0 | 6(1.8) | 4(5.8) | 2(0.8) | 0.080 |
| T1 | 24(7.2) | 5(7.2) | 19(7.2) | |
| T2 | 63(18.9) | 13(18.8) | 50(18.9) | |
| T3 | 196(58.9) | 40(58.0) | 156(59.1) | |
| T4 | 44(13.2) | 7(10.1) | 37(14.0) | |
| Nodal metastasis (N) # | ||||
| N0 | 197(51.6) | 49(62.8) | 148(48.7) | 0.026 |
| N+ | 185(48.4) | 29(37.2) | 156(51.3) | |
| TNM stage# | ||||
| 0-II | 143(39.9) | 33(46.5) | 110(38.3) | 0.183 |
| III | 175(48.9) | 34(47.9) | 141(49.1) | |
| IV | 40(11.2) | 4(5.6) | 36(12.5) | |
* Others mainly include high-grade dysplasia, carcinoma in situ
#According to the 7th IUCC/AJCC staging system, location of the primary cancer site was defined by the position of the upper (proximal) edge of the tumor in the esophagus, and the remaining missing patients were ominous
@The statistical method was chi-square test.