Skip to main content
. 2016 Oct 27;8(18):30477–30494. doi: 10.18632/oncotarget.12955

Table 2. Investigated Clinicopathological variables for neoadjuvant chemotherapy in patients with LAGC.

Clinicopathological variable Brief summarization Reference
Hemoglobin level Hemoglobin level was related to the response [41]
Lymph node metastasis The presence of lymph node metastasis was correlated with NAC Chemosensitivity [41]
Tumor size Tumor size was independent predictors of tumor regression [28]
Tumor localization Tumor localization in the middle third of the stomach was related to the response [29]
Differentiation Well tumor differentiation were related to better histopathological response [29]
Laure's classification Intestinal tumor type according to Lauren's classification accurately predicts histopathological response and prognosis in neoadjuvant treated LAGC [29]
Serum low-density lipoprotein Higher low-density lipoprotein is statistically significant with histopathological response in LAGC patients undergoing NAC [42]
Endoscopy(second evaluation) Re-biopsies taken after NAC do not help in determining the response, since the biopsy might have been taken from an area of localized complete response [15]
Laparoscopy(re-staging) Staging laparoscopy might detect not only pre-existing condition but also disease progression during NAC [43]