Table 1. Arterial blood gases at Start and End.
nIAP | IAH | ||||
---|---|---|---|---|---|
Time point | PCV | PSV | PCV | PSV | |
PaO2/FiO2 | Start | 304 ± 174 | 341 ± 155 | 280 ± 143 | 245 ± 146 |
End | 334 ± 115 | 429 ± 132 | 329 ± 112 | 421 ± 92* | |
pHa | Start | 7.31 ± 0.08 | 7.31 ± 0.07 | 7.31 ± 0.04 | 7.35 ± 0.09 |
End | 7.22 ± 0.05* | 7.31 ± 0.05# | 7.20 ± 0.06* | 7.30 ± 0.03# | |
PaCO2 (mmHg) | Start | 44.9 ± 15.8 | 35.2 ± 14.0 | 46.6 ± 15.7 | 39.1 ± 12.4 |
End | 43.5 ± 17.5 | 39.8 ± 11.3 | 50.5 ± 16.8 | 47.7 ± 8.5 |
IAH, intra-abdominal hypertension; nIAP, normal intra-abdominal pressure; PCV, pressure-controlled ventilation; PSV, pressure support ventilation; Start, after sham surgery (nIAP) or IAH induction; End, nIAP or IAH after 1 h mechanical ventilation with PCV or PSV; PaO2/FiO2, arterial oxygen partial pressure divided by fraction of inspired oxygen; pHa, arterial pH; PaCO2, arterial carbon dioxide partial pressure. Comparisons were performed by two-way repeated-measures ANOVA followed by Bonferroni’s post-hoc test. Values are given as mean ± standard deviation of 6 animals/group.
*Significantly different from Start (p<0.05).
#Significantly different from PCV group at the corresponding time point (p<0.05).